Cefoperazone Sodium and Sulbactam Sodium Mixture Ratio 1:1 2:1

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    2017-12-26 00:25

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Cefoperazone Sodium and Sulbactam Sodium Mixture                                             

Product

Cefoperazone Sodium and Sulbactam Sodium   Mixture

Ratio:

1:1

2:1

Synonyms:  

Cefoperazone Sodium Sulbactam Sodium

Characteristics:

White powder.

 

Usage: Cefoperazone Sodium and Sulbactam Sodium Mixure.  Because Sulbactam also binds with some penicillin-binding proteins, sensitive strains are also often rendered more susceptible to cefoperazone  together with sulbactam than to cefoperazone alone.

 

Certificate of Analysis: Cefoperazone Sodium and Sulbactam Sodium (1:1)

Product

Cefoperazone   Sodium and Sulbactam Sodium (1:1)

Testing Item

Standard

Result

Appearance

White   to slightly yellow powder or crystalline powder.

Almost   white powder

Identification   A

The HPLC RT should correspond to that of reference standard.

Complies

Identification   B

Yields   the flame reaction of sodium.

Complies

pH

3.5   ~ 6.5

5.3

Clarity   of solution

≤   1#

<   0.25#

Color   of solution

≤   4# (Y or YG)

<   2Y#

Water

≤   4.0%

2.1%

Related   Substances

Impurity   A≤ 1.5%

Any   single impurity ≤1.5%

Other   total impurities≤ 5.0%

0.1%

0.4%

1.4%

Visible   Particles

Conforms

Conforms

Paticulate   matter

≥10   μm ≤ 6000 particle/4.0g

≥25   μm ≤ 600 particle/4.0g

165   particle/4.0g

0   particle/4.0g

Bacterial   Endotoxins

≤   0.050EU/mg

0.005EU/mg

Sterility

Should   meet the requirement

Complies

Assay

Cefoperazone   ≥435ug/mg

Sulbactam   ≥445ug/mg

462.5ug/mg

462.5ug/mg

Ratio   of Cefoperazone Sodium and Sulbactam Sodium

0.97~1.05

1.00